Below is a list of feature publications from our lab.
The full list of articles can be found on PubMed.
Functional annotation of the human PTSD methylome identifies tissue-specific epigenetic variation across subcortical brain regions. Li H, Wang J, Cruz DA, Modliszewski JL, Corcoran DL, Martínez-Magaña JJ, Montalvo-Ortiz JL, Roache JD, Averill LA, Young-McCaughan S, Shiroma PR, Traumatic Stress Brain Research Group, Lewis DA, Glausier J, Holtzheimer P, Friedman MJ, Zhang J, Peterson AL, Abdallah CG, Zhang X, Xu K, Krystal JH, Duman RS, Zhao H, Williamson DE, Girgenti MJ. medRxiv. 2023.04.18.23288704;
Integrating genetics and transcriptomics to study major depressive disorder: a conceptual framework, bioinformatic approaches, and recent findings. Hicks EM, Seah C, Cote A, Marchese S, Brennand KJ, Nestler EJ, Girgenti MJ, Huckins LM. Translational Psychiatry. 2023 Apr 19;13(1):129. doi: 10.1038/s41398-023-02412-7. PMID: 37076454; PMCID: PMC10115809.
Molecular and cellular evolution of the primate dorsolateral prefrontal cortex. Ma S, Skarica M, Li Q, Xu C, Risgaard RD, Tebbenkamp ATN, Mato-Blanco X, Kovner R, Krsnik Ž, de Martin X, Luria V, Martí-Pérez X, Liang D, Karger A, Schmidt DK, Gomez-Sanchez Z, Qi C, Gobeske KT, Pochareddy S, Debnath A, Hottman CJ, Spurrier J, Teo L, Boghdadi AG, Homman-Ludiye J, Ely JJ, Daadi EW, Mi D, Daadi M, Marín O, Hof PR, Rasin MR, Bourne J, Sherwood CC, Santpere G, Girgenti MJ, Strittmatter SM, Sousa AMM, Sestan N. Science. 2022 Sep 30;377(6614):eabo7257. doi: 10.1126/science.abo7257. Epub 2022 Sep 30. PMID: 36007006; PMCID: PMC9614553.
Posttraumatic Stress Disorder Brain Transcriptomics: Convergent Genomic Signatures Across Biological Sex. Wang J, Zhao H, Girgenti MJ. Biological Psychiatry. 2022 Jan 1;91(1):6-13.
Transcriptomic organization of the human brain in post-traumatic stress disorder. Girgenti MJ, Wang J, Ji D, Cruz DA; Traumatic Stress Brain Research Group, Stein MB, Gelernter J, Young KA, Huber BR, Williamson DE, Friedman MJ, Krystal JH, Zhao H, Duman RS. Nature Neuroscience. 2021 Jan;24(1):24-33.
PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies. Bhatt S, Hillmer AT, Girgenti MJ, Rusowicz A, Kapinos M, Nabulsi N, Huang Y, Matuskey D, Angarita GA, Esterlis I, Davis MT, Southwick SM, Friedman MJ; Traumatic Stress Brain Study Group, Duman RS, Carson RE, Krystal JH, Pietrzak RH, Cosgrove KP.
Nature Communication. 2020 May 12;11(1):2360.
Prefrontal cortex interneurons display dynamic sex-specific stress-induced transcriptomes. Girgenti MJ, Wohleb ES, Mehta S, Ghosal S, Fogaca MV, Duman RS.Translational Psychiatry. 2019 Nov 11;9(1):292.
Transcriptome Alterations in Post-traumatic Stress Disorder. Girgenti MJ and Duman RS.Biological Psychiatry. 2018 May 16;83(10):840-848.
Ketamine accelerates fear extinction via mTORC1 signaling. Girgenti MJ, Ghosal S, LoPresto D, Taylor JR, Duman RS. Neurobiology of Disease. 2017 Apr;100:1-8.