The Girgenti Lab @Yale Psychiatry
Translating molecular mechanisms to disease etiology
PTSD is a severe, debilitating, and prevalent disorder occurring in the aftermath of significant trauma exposure. The neurobiology of PTSD with regard to trauma-associated genetic, epigenetic, and transcriptional mechanisms is poorly understood and many critical questions remain. Recently, our group published the first large genomic study of the PTSD frontal cortex, one of the key components of the fear neural circuit, arguably among the best-understood circuits in neuroscience.